Burkholderia pseudomallei K96243, BPSL2192 (aceB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2192
Name
aceB
Replicon chromosome 1
Genomic location 2630844 - 2632436 (+ strand)

Cross-References

RefSeq YP_108787.1
GI 53719801
Entrez 3092656
GI 53719801
INSDC CAH36194.1
NCBI Locus Tag BPSL2192
RefSeq YP_108787.1,GeneID
UniParc UPI000043B2B3
UniProtKB Acc Q63SX9
UniProtKB ID Q63SX9_BURPS
UniRef100 UniRef100_Q63SX9
UniRef50 UniRef50_P95329
UniRef90 UniRef90_B4ECR3

Product

Feature Type CDS
Coding Frame 1
Product Name
malate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -6.68
Kyte-Doolittle Hydrophobicity Value -0.304
Molecular Weight (kDa) 59220.0
Isoelectric Point (pI) 5.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 160 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001941 (648 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2192
Search term: aceB
Search term: malate synthase

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268