Burkholderia pseudomallei K96243, BPSL2169 (dapD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2169
Name
dapD
Replicon chromosome 1
Genomic location 2606741 - 2607568 (+ strand)

Cross-References

RefSeq YP_108764.1
GI 53719778
Entrez 3091791
GI 53719778
INSDC CAH36171.1
NCBI Locus Tag BPSL2169
RefSeq YP_108764.1,GeneID
UniParc UPI000043B29C
UniProtKB Acc Q63T02
UniProtKB ID DAPD_BURPS
UniRef100 UniRef100_A3MKV6
UniRef50 UniRef50_P56220
UniRef90 UniRef90_A3MKV6

Product

Feature Type CDS
Coding Frame 1
Product Name
2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (30.5 kDa, pI 6.00, PMID:21960737)
Charge (pH 7) -3.13
Kyte-Doolittle Hydrophobicity Value -0.022
Molecular Weight (kDa) 29507.4
Isoelectric Point (pI) 5.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3TK8 TRANSFERASE 08/25/11 Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 339 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001919 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2169
Search term: dapD

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268