Burkholderia pseudomallei K96243, BPSL2129 (guaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2129
Name
guaB
Replicon chromosome 1
Genomic location 2557817 - 2559277 (- strand)

Cross-References

RefSeq YP_108726.1
GI 53719740
Entrez 3092041
GI 53719740
INSDC CAH36132.1
NCBI Locus Tag BPSL2129
RefSeq YP_108726.1,GeneID
UniParc UPI000043B276
UniProtKB Acc Q63T40
UniProtKB ID Q63T40_BURPS
UniRef100 UniRef100_A0A069B687
UniRef50 UniRef50_P21879
UniRef90 UniRef90_Q2SWW9

Product

Feature Type CDS
Coding Frame 1
Product Name
inosine 5'-monophosphate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) 2.75
Kyte-Doolittle Hydrophobicity Value 0.003
Molecular Weight (kDa) 51898.4
Isoelectric Point (pI) 7.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 638 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001881 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2129
Search term: guaB

Human Homologs

Ensembl 97, assembly GRCh38.p12
inosine monophosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6052]
E-value: 5.6e-97
Percent Identity: 42.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
inosine monophosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6052]
E-value: 5.6e-97
Percent Identity: 42.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
inosine monophosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6052]
E-value: 5.6e-97
Percent Identity: 42.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268