Burkholderia pseudomallei K96243, BPSL2012 (glnS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2012
Name
glnS
Replicon chromosome 1
Genomic location 2400830 - 2402539 (+ strand)

Cross-References

RefSeq YP_108610.1
GI 53719624
Entrez 3091627
GI 53719624
INSDC CAH36011.1
NCBI Locus Tag BPSL2012
RefSeq YP_108610.1,GeneID
UniParc UPI000043B203
UniProtKB Acc Q63TF6
UniProtKB ID Q63TF6_BURPS
UniRef100 UniRef100_Q3JT90
UniRef50 UniRef50_A4SZM1
UniRef90 UniRef90_Q3JT90

Product

Feature Type CDS
Coding Frame 1
Product Name
glutaminyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -9.26
Kyte-Doolittle Hydrophobicity Value -0.644
Molecular Weight (kDa) 65219.5
Isoelectric Point (pI) 6.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 663 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001232 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2012
Search term: glnS

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]
E-value: 1.6e-124
Percent Identity: 45.7
Ensembl 97, assembly GRCh38.p12
glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]
E-value: 1.6e-124
Percent Identity: 45.7
Ensembl 97, assembly GRCh38.p12
glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]
E-value: 1.6e-124
Percent Identity: 45.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268