Burkholderia pseudomallei K96243, BPSL1981 (galU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1981
Name
galU
Replicon chromosome 1
Genomic location 2362538 - 2363419 (+ strand)

Cross-References

RefSeq YP_108579.1
GI 53719593
Entrez 3092713
GI 53719593
INSDC CAH35980.1
NCBI Locus Tag BPSL1981
RefSeq YP_108579.1,GeneID
UniParc UPI000043B1E4
UniProtKB Acc Q63TI7
UniProtKB ID Q63TI7_BURPS
UniRef100 UniRef100_A0A069B0N6
UniRef50 UniRef50_Q2SVA0
UniRef90 UniRef90_Q2SVA0

Product

Feature Type CDS
Coding Frame 1
Product Name
UTP-glucose-1-phosphate uridylyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -7.16
Kyte-Doolittle Hydrophobicity Value -0.130
Molecular Weight (kDa) 32404.0
Isoelectric Point (pI) 5.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5VE7 TRANSFERASE 04/04/17 Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from Burkholderia ambifaria in complex with UTP BURKHOLDERIA AMBIFARIA (STRAIN MC40-6) 2.3 X-RAY DIFFRACTION 94.1
5J49 TRANSFERASE 03/31/16 Crystal structure of UDP-glucose pyrophosporylase / UTP-glucose-1-phosphate uridylyltransferase from Burkholderia xenovorans BURKHOLDERIA XENOVORANS (STRAIN LB400) 1.8 X-RAY DIFFRACTION 90.0
5VCT TRANSFERASE 03/31/17 Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from Burkholderia ambifaria BURKHOLDERIA AMBIFARIA (STRAIN MC40-6) 1.9 X-RAY DIFFRACTION 94.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 621 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001267 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1981
Search term: galU

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268