Burkholderia pseudomallei K96243, BPSL1945 (thrS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1945
Name
thrS
Replicon chromosome 1
Genomic location 2314737 - 2316644 (- strand)

Cross-References

RefSeq YP_108544.1
GI 53719558
Entrez 3092747
GI 53719558
INSDC CAH35944.1
NCBI Locus Tag BPSL1945
RefSeq YP_108544.1,GeneID
UniParc UPI000043B1C1
UniProtKB Acc Q63TM2
UniProtKB ID SYT_BURPS
UniRef100 UniRef100_A3MJT8
UniRef50 UniRef50_Q83C10
UniRef90 UniRef90_Q2SVD8

Product

Feature Type CDS
Coding Frame 1
Product Name
threonyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -8.36
Kyte-Doolittle Hydrophobicity Value -0.451
Molecular Weight (kDa) 72264.6
Isoelectric Point (pI) 6.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001306 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1945
Search term: thrS

Human Homologs

Ensembl 97, assembly GRCh38.p12
threonyl-tRNA synthetase like 2 [Source:HGNC Symbol;Acc:HGNC:24728]
E-value: 3.1e-132
Percent Identity: 39.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268