Burkholderia pseudomallei K96243, BPSL1911 (typA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1911
Name
typA
Replicon chromosome 1
Genomic location 2276550 - 2278376 (- strand)

Cross-References

RefSeq YP_108511.1
GI 53719525
Entrez 3091717
GI 53719525
INSDC CAH35911.1
NCBI Locus Tag BPSL1911
RefSeq YP_108511.1,GeneID
UniParc UPI000043B1A2
UniProtKB Acc Q63TQ5
UniProtKB ID Q63TQ5_BURPS
UniRef100 UniRef100_A0A095Q5R8
UniRef50 UniRef50_P72749
UniRef90 UniRef90_Q39H23

Product

Feature Type CDS
Coding Frame 1
Product Name
GTP-binding protein
Synonyms
Evidence for Translation
Charge (pH 7) -14.88
Kyte-Doolittle Hydrophobicity Value -0.255
Molecular Weight (kDa) 67497.5
Isoelectric Point (pI) 5.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001335 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1911
Search term: typA

Human Homologs

Ensembl 97, assembly GRCh38.p12
elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789]
E-value: 3.5e-24
Percent Identity: 43.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789]
E-value: 3.5e-24
Percent Identity: 43.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268