Burkholderia pseudomallei K96243, BPSL1909 (sucA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1909
Name
sucA
Replicon chromosome 1
Genomic location 2271756 - 2274620 (- strand)

Cross-References

RefSeq YP_108509.1
GI 53719523
Entrez 3094519
GI 53719523
INSDC CAH35909.1
NCBI Locus Tag BPSL1909
RefSeq YP_108509.1,GeneID
UniParc UPI000043B1A0
UniProtKB Acc Q63TQ7
UniProtKB ID Q63TQ7_BURPS
UniRef100 UniRef100_A0A069B799
UniRef50 UniRef50_P20707
UniRef90 UniRef90_Q2SVH6

Product

Feature Type CDS
Coding Frame 1
Product Name
2-oxoglutarate dehydrogenase E1
Synonyms
Evidence for Translation
Charge (pH 7) -6.92
Kyte-Doolittle Hydrophobicity Value -0.393
Molecular Weight (kDa) 106450.5
Isoelectric Point (pI) 6.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 367 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001336 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1909
Search term: sucA

Human Homologs

Ensembl 97, assembly GRCh38.p12
oxoglutarate dehydrogenase like [Source:HGNC Symbol;Acc:HGNC:25590]
E-value: 1.2e-196
Percent Identity: 41.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268