Burkholderia pseudomallei K96243, BPSL1908 (sucB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1908
Name
sucB
Replicon chromosome 1
Genomic location 2270344 - 2271621 (- strand)

Cross-References

RefSeq YP_108508.1
GI 53719522
Entrez 3093009
GI 53719522
INSDC CAH35908.1
NCBI Locus Tag BPSL1908
RefSeq YP_108508.1,GeneID
UniParc UPI000043B19F
UniProtKB Acc Q63TQ8
UniProtKB ID Q63TQ8_BURPS
UniRef100 UniRef100_A0A069B7M6
UniRef50 UniRef50_A1V3M4
UniRef90 UniRef90_A1V3M4

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide succinyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -3.78
Kyte-Doolittle Hydrophobicity Value 0.057
Molecular Weight (kDa) 44313.5
Isoelectric Point (pI) 5.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 514 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001337 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1908
Search term: sucB

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydrolipoamide S-succinyltransferase [Source:HGNC Symbol;Acc:HGNC:2911]
E-value: 3.5e-71
Percent Identity: 43.8

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268