Burkholderia pseudomallei K96243, BPSL1874

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1874
Name
Replicon chromosome 1
Genomic location 2227421 - 2229955 (- strand)

Cross-References

RefSeq YP_108473.1
GI 53719487
Entrez 3091947
GI 53719487
NCBI Locus Tag BPSL1874
RefSeq YP_108473.1,GeneID
UniProtKB Acc Q63TU3
UniProtKB ID Q63TU3_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
ribonuclease
Synonyms
Evidence for Translation
Charge (pH 7) 24.04
Kyte-Doolittle Hydrophobicity Value -0.424
Molecular Weight (kDa) 93866.3
Isoelectric Point (pI) 9.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 541 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001373 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1874
Search term: ribonuclease

Human Homologs

Ensembl 97, assembly GRCh38.p12
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:20604]
E-value: 6.1e-51
Percent Identity: 28.7

Human Homologs

Ensembl 97, assembly GRCh38.p12
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:20604]
E-value: 6.1e-51
Percent Identity: 28.7

Human Homologs

Ensembl 97, assembly GRCh38.p12
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:20604]
E-value: 6.1e-51
Percent Identity: 28.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268