Burkholderia pseudomallei K96243, BPSL1778

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1778
Name
Replicon chromosome 1
Genomic location 2104329 - 2114201 (- strand)

Cross-References

RefSeq YP_108378.1
GI 53719392
Entrez 3092438
GI 53719392
INSDC CAH35777.1
NCBI Locus Tag BPSL1778
RefSeq YP_108378.1,GeneID
UniParc UPI000043B11D
UniProtKB Acc Q63U38
UniProtKB ID Q63U38_BURPS
UniRef100 UniRef100_Q63U38
UniRef50 UniRef50_C4KXW7
UniRef90 UniRef90_C4KXW7

Product

Feature Type CDS
Coding Frame 1
Product Name
siderophore related no-ribosomal peptide synthase
Synonyms
Evidence for Translation
Charge (pH 7) -27.51
Kyte-Doolittle Hydrophobicity Value 0.051
Molecular Weight (kDa) 348645.1
Isoelectric Point (pI) 6.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 582 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001460 (2297 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1778

Human Homologs

Ensembl 97, assembly GRCh38.p12
acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571]
E-value: 1.4e-05
Percent Identity: 20.7
Ensembl 97, assembly GRCh38.p12
acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571]
E-value: 1.4e-05
Percent Identity: 20.7
Ensembl 97, assembly GRCh38.p12
acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571]
E-value: 1.4e-05
Percent Identity: 20.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268