Burkholderia pseudomallei K96243, BPSL1754

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1754
Name
Replicon chromosome 1
Genomic location 2066841 - 2068412 (+ strand)

Cross-References

RefSeq YP_108354.1
GI 53719368
Entrez 3092319
GI 53719368
NCBI Locus Tag BPSL1754
RefSeq YP_108354.1,GeneID
UniProtKB Acc Q63U62
UniProtKB ID Q63U62_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein
Synonyms
Evidence for Translation
Charge (pH 7) 5.56
Kyte-Doolittle Hydrophobicity Value -0.346
Molecular Weight (kDa) 58194.8
Isoelectric Point (pI) 8.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 131 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019629 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1754
Search term: lipoprotein

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268