Burkholderia pseudomallei K96243, BPSL1744 (arcB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1744
Name
arcB
Replicon chromosome 1
Genomic location 2056648 - 2057658 (+ strand)

Cross-References

RefSeq YP_108344.1
GI 53719358
Entrez 3092910
GI 53719358
INSDC CAH35743.1
NCBI Locus Tag BPSL1744
RefSeq YP_108344.1,GeneID
UniParc UPI000043B0FB
UniProtKB Acc Q63U72
UniProtKB ID OTCC_BURPS
UniRef100 UniRef100_Q63U72
UniRef50 UniRef50_P08308
UniRef90 UniRef90_Q63U72

Product

Feature Type CDS
Coding Frame 1
Product Name
ornithine carbamoyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -2.78
Kyte-Doolittle Hydrophobicity Value -0.348
Molecular Weight (kDa) 38016.9
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 643 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019625 (439 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1744
Search term: arcB

Human Homologs

Ensembl 97, assembly GRCh38.p12
ornithine carbamoyltransferase [Source:HGNC Symbol;Acc:HGNC:8512]
E-value: 4.5e-53
Percent Identity: 39.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268