Burkholderia pseudomallei K96243, BPSL1527 (tex)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1527
Name
tex
Replicon chromosome 1
Genomic location 1767550 - 1769874 (- strand)

Cross-References

RefSeq YP_108147.1
GI 53719161
Entrez 3091541
GI 53719161
INSDC CAH35528.1
NCBI Locus Tag BPSL1527
RefSeq YP_108147.1,GeneID
UniParc UPI000043B038
UniProtKB Acc Q63UR9
UniProtKB ID Q63UR9_BURPS
UniRef100 UniRef100_Q3JRR9
UniRef50 UniRef50_Q45388
UniRef90 UniRef90_Q39FS3

Product

Feature Type CDS
Coding Frame 1
Product Name
transcription accessory protein
Synonyms
Evidence for Translation
Charge (pH 7) -3.89
Kyte-Doolittle Hydrophobicity Value -0.297
Molecular Weight (kDa) 84583.4
Isoelectric Point (pI) 6.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 606 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001635 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1527
Search term: tex

Human Homologs

Ensembl 97, assembly GRCh38.p12
S1 RNA binding domain 1 [Source:HGNC Symbol;Acc:HGNC:25521]
E-value: 7.8e-101
Percent Identity: 33.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268