Burkholderia pseudomallei K96243, BPSL1359 (pstS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1359
Name
pstS
Replicon chromosome 1
Genomic location 1587905 - 1588933 (+ strand)

Cross-References

RefSeq YP_107984.1
GI 53718998
Entrez 3093141
GI 53718998
INSDC CAH35357.1
NCBI Locus Tag BPSL1359
RefSeq YP_107984.1,GeneID
UniParc UPI000043AF96
UniProtKB Acc Q63V82
UniProtKB ID Q63V82_BURPS
UniRef100 UniRef100_A0A069B6I1
UniRef50 UniRef50_P45192
UniRef90 UniRef90_Q2SUW4

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphate transport system, substrate-binding exported periplasmic protein
Synonyms
Evidence for Translation
Charge (pH 7) 5.47
Kyte-Doolittle Hydrophobicity Value -0.099
Molecular Weight (kDa) 36156.0
Isoelectric Point (pI) 9.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5WNN PHOSPHATE BINDING PROTEIN 08/01/17 Crystal structure of Phosphate-binding protein PstS protein from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI (STRAIN K96243) 1.85 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 337 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001137 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1359
Search term: pstS

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268