Burkholderia pseudomallei K96243, BPSL1224 (nuoN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1224
Name
nuoN
Replicon chromosome 1
Genomic location 1410200 - 1411672 (+ strand)

Cross-References

RefSeq YP_107846.1
GI 53718860
Entrez 3093346
GI 53718860
INSDC CAH35219.1
NCBI Locus Tag BPSL1224
RefSeq YP_107846.1,GeneID
UniParc UPI000043AF0C
UniProtKB Acc Q63VM0
UniProtKB ID Q63VM0_BURPS
UniRef100 UniRef100_A0A069B3P6
UniRef50 UniRef50_Q0A788
UniRef90 UniRef90_N0ANW0

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase subunit N
Synonyms
Evidence for Translation
Charge (pH 7) 3.64
Kyte-Doolittle Hydrophobicity Value 0.921
Molecular Weight (kDa) 52568.1
Isoelectric Point (pI) 8.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 557 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002123 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1224
Search term: nuoN

Human Homologs

Ensembl 97, assembly GRCh38.p12
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 [Source:HGNC Symbol;Acc:HGNC:7456]
E-value: 5.0e-13
Percent Identity: 25.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268