Burkholderia pseudomallei K96243, BPSL1213 (nuoC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1213
Name
nuoC
Replicon chromosome 1
Genomic location 1397713 - 1398315 (+ strand)

Cross-References

RefSeq YP_107835.1
GI 53718849
Entrez 3092227
GI 53718849
INSDC CAH35208.1
NCBI Locus Tag BPSL1213
RefSeq YP_107835.1,GeneID
UniParc UPI000043AF01
UniProtKB Acc Q63VN1
UniProtKB ID NUOC_BURPS
UniRef100 UniRef100_A3MIA3
UniRef50 UniRef50_Q9K1C1
UniRef90 UniRef90_A3MIA3

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase subunit C
Synonyms
Evidence for Translation
Charge (pH 7) -6.07
Kyte-Doolittle Hydrophobicity Value -0.217
Molecular Weight (kDa) 22764.6
Isoelectric Point (pI) 4.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 452 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002134 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1213
Search term: nuoC

Human Homologs

Ensembl 97, assembly GRCh38.p12
NADH:ubiquinone oxidoreductase core subunit S3 [Source:HGNC Symbol;Acc:HGNC:7710]
E-value: 2.5e-35
Percent Identity: 47.1
Ensembl 97, assembly GRCh38.p12
NADH:ubiquinone oxidoreductase core subunit S3 [Source:HGNC Symbol;Acc:HGNC:7710]
E-value: 2.5e-35
Percent Identity: 47.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268