Burkholderia pseudomallei K96243, BPSL0906 (ileS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0906
Name
ileS
Replicon chromosome 1
Genomic location 1056325 - 1059162 (- strand)

Cross-References

RefSeq YP_107533.1
GI 53718547
Entrez 3092378
GI 53718547
INSDC CAH34900.1
NCBI Locus Tag BPSL0906
RefSeq YP_107533.1,GeneID
UniParc UPI000043ADD5
UniProtKB Acc Q63WI3
UniProtKB ID SYI1_BURPS
UniRef100 UniRef100_Q63WI3
UniRef50 UniRef50_Q62HL4
UniRef90 UniRef90_Q62HL4

Product

Feature Type CDS
Coding Frame 1
Product Name
isoleucyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -10.06
Kyte-Doolittle Hydrophobicity Value -0.361
Molecular Weight (kDa) 105708.8
Isoelectric Point (pI) 6.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002379 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0906
Search term: ileS

Human Homologs

Ensembl 97, assembly GRCh38.p12
isoleucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29685]
E-value: 2.4e-144
Percent Identity: 36.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268