Burkholderia pseudomallei K96243, BPSL0906 (ileS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0906
Name
ileS
Replicon chromosome 1
Genomic location 1056325 - 1059162 (- strand)

Cross-References

RefSeq YP_107533.1
GI 53718547
Entrez 3092378
GI 53718547
INSDC CAH34900.1
NCBI Locus Tag BPSL0906
RefSeq YP_107533.1,GeneID
UniParc UPI000043ADD5
UniProtKB Acc Q63WI3
UniProtKB ID SYI1_BURPS
UniRef100 UniRef100_Q63WI3
UniRef50 UniRef50_Q62HL4
UniRef90 UniRef90_Q62HL4

Product

Feature Type CDS
Coding Frame 1
Product Name
isoleucyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -10.06
Kyte-Doolittle Hydrophobicity Value -0.361
Molecular Weight (kDa) 105708.8
Isoelectric Point (pI) 6.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002379 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0906
Search term: ileS

Human Homologs

Ensembl 97, assembly GRCh38.p12
isoleucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29685]
E-value: 2.4e-144
Percent Identity: 36.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268