Burkholderia pseudomallei K96243, BPSL0874

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0874
Name
Replicon chromosome 1
Genomic location 1014452 - 1015210 (- strand)

Cross-References

RefSeq YP_107499.1
GI 53718513
Entrez 3091633
GI 53718513
INSDC CAH34866.1
NCBI Locus Tag BPSL0874
RefSeq YP_107499.1,GeneID
UniParc UPI000043ADB4
UniProtKB Acc Q63WL7
UniProtKB ID Q63WL7_BURPS
UniRef100 UniRef100_A3N6K3
UniRef50 UniRef50_B0BMW2
UniRef90 UniRef90_A3N6K3

Product

Feature Type CDS
Coding Frame 1
Product Name
short-chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) 0.18
Kyte-Doolittle Hydrophobicity Value 0.273
Molecular Weight (kDa) 25917.9
Isoelectric Point (pI) 7.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4XGN OXIDOREDUCTASE 12/31/14 Crystal structure of 3-hydroxyacyl-CoA dehydrogenase in complex with NAD from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 1.65 X-RAY DIFFRACTION 97.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 648 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002412 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0874

Human Homologs

Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800]
E-value: 1.3e-68
Percent Identity: 58.3

References

No references are associated with this feature.