Burkholderia pseudomallei K96243, BPSL0872

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL0872
Name
Replicon	chromosome 1
Genomic location	1011781 - 1013331 (+ strand)

Cross-References

RefSeq	YP_107497.1
GI	53718511
Entrez	3093782
GI	53718511
INSDC	CAH34864.1
NCBI Locus Tag	BPSL0872
RefSeq	YP_107497.1,GeneID
UniParc	UPI000043ADB2
UniProtKB Acc	Q63WL9
UniProtKB ID	Q63WL9_BURPS
UniRef100	UniRef100_A3NS84
UniRef50	UniRef50_Q2T0K7
UniRef90	UniRef90_Q2T0K7

Product

Feature Type	CDS
Coding Frame	1
Product Name	MviN-like protein
Synonyms
Evidence for Translation
Charge (pH 7)	25.36
Kyte-Doolittle Hydrophobicity Value	0.824
Molecular Weight (kDa)	55498.5
Isoelectric Point (pI)	10.82

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database	Victors : 2006
Category
Evidence	ECO:0000015 mutant phenotype evidence
Host Organism	Mesocricetus auratus
Notes	BPSLO872 (mviN) mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells
Reference	17189432

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 471 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002414 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL0872 Search term: MviN-like protein

Human Homologs

References