Burkholderia pseudomallei K96243, BPSL0820 (flhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0820
Name
flhA
Replicon chromosome 1
Genomic location 954204 - 955310 (+ strand)

Cross-References

RefSeq YP_107444.1
GI 53718458
Entrez 3091474
GI 53718458
INSDC CAH34811.1
NCBI Locus Tag BPSL0820
RefSeq YP_107444.1,GeneID
UniParc UPI000043AD7D
UniProtKB Acc Q63WS2
UniProtKB ID Q63WS2_BURPS
UniRef100 UniRef100_Q63WS2
UniRef50 UniRef50_P46415
UniRef90 UniRef90_Q13UL8

Product

Feature Type CDS
Coding Frame 1
Product Name
glutathione-dependent formaldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -2.37
Kyte-Doolittle Hydrophobicity Value 0.046
Molecular Weight (kDa) 39580.4
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 554 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005368 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0820
Search term: flhA

Human Homologs

Ensembl 97, assembly GRCh38.p12
alcohol dehydrogenase 5 (class III), chi polypeptide [Source:HGNC Symbol;Acc:HGNC:253]
E-value: 1.1e-134
Percent Identity: 61.3

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268