Burkholderia pseudomallei K96243, BPSL0799 (hemH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0799
Name
hemH
Replicon chromosome 1
Genomic location 927407 - 928297 (+ strand)

Cross-References

RefSeq YP_107424.1
GI 53718438
Entrez 3094817
GI 53718438
INSDC CAH34791.1
NCBI Locus Tag BPSL0799
RefSeq YP_107424.1,GeneID
UniParc UPI000043AD6A
UniProtKB Acc Q63WU2
UniProtKB ID Q63WU2_BURPS
UniRef100 UniRef100_A0A069B2F2
UniRef50 UniRef50_P43851
UniRef90 UniRef90_F2L8Z8

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoribosylaminoimidazole-succinocarboxamide synthase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (32.7 kDa, pI 5.17, PMID:21960737)
Charge (pH 7) -7.82
Kyte-Doolittle Hydrophobicity Value -0.290
Molecular Weight (kDa) 32839.0
Isoelectric Point (pI) 5.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 436 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002484 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0799
Search term: hemH

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268