Burkholderia pseudomallei K96243, BPSL0797 (pykA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0797
Name
pykA
Replicon chromosome 1
Genomic location 924436 - 925872 (+ strand)

Cross-References

RefSeq YP_107422.1
GI 53718436
Entrez 3093639
GI 53718436
INSDC CAH34789.1
NCBI Locus Tag BPSL0797
RefSeq YP_107422.1,GeneID
UniParc UPI000043AD68
UniProtKB Acc Q63WU4
UniProtKB ID Q63WU4_BURPS
UniRef100 UniRef100_A0A069B5B5
UniRef50 UniRef50_Q2T0S9
UniRef90 UniRef90_Q2T0S9

Product

Feature Type CDS
Coding Frame 1
Product Name
pyruvate kinase
Synonyms
Evidence for Translation
Charge (pH 7) -5.91
Kyte-Doolittle Hydrophobicity Value -0.027
Molecular Weight (kDa) 51369.7
Isoelectric Point (pI) 6.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 614 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002486 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0797
Search term: pykA
Search term: pyruvate kinase

Human Homologs

Ensembl 97, assembly GRCh38.p12
pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]
E-value: 4.7e-72
Percent Identity: 36.7
Ensembl 97, assembly GRCh38.p12
pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]
E-value: 4.7e-72
Percent Identity: 36.7
Ensembl 97, assembly GRCh38.p12
pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]
E-value: 4.7e-72
Percent Identity: 36.7
Ensembl 97, assembly GRCh38.p12
pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]
E-value: 4.7e-72
Percent Identity: 36.7

References

No references are associated with this feature.