Burkholderia pseudomallei K96243, BPSL0796 (pgk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0796
Name
pgk
Replicon chromosome 1
Genomic location 922908 - 924101 (+ strand)

Cross-References

RefSeq YP_107421.1
GI 53718435
Entrez 3092746
GI 53718435
INSDC CAH34788.1
NCBI Locus Tag BPSL0796
RefSeq YP_107421.1,GeneID
UniParc UPI000043AD67
UniProtKB Acc Q63WU5
UniProtKB ID Q63WU5_BURPS
UniRef100 UniRef100_Q63WU5
UniRef50 UniRef50_Q9K1R0
UniRef90 UniRef90_B2JDD4

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoglycerate kinase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (28.9 kDa, pI 5.18, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (43.7 kDa, pI 5.72, PMID:21960737)
Charge (pH 7) -4.87
Kyte-Doolittle Hydrophobicity Value 0.099
Molecular Weight (kDa) 41232.9
Isoelectric Point (pI) 5.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 664 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002487 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0796
Search term: pgk

Human Homologs

Ensembl 97, assembly GRCh38.p12
phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898]
E-value: 4.7e-70
Percent Identity: 42.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268