Burkholderia pseudomallei K96243, BPSL0780 (sucD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0780
Name
sucD
Replicon chromosome 1
Genomic location 907685 - 908566 (+ strand)

Cross-References

RefSeq YP_107405.1
GI 53718419
Entrez 3092908
GI 53718419
INSDC CAH34772.1
NCBI Locus Tag BPSL0780
RefSeq YP_107405.1,GeneID
UniParc UPI000043AD57
UniProtKB Acc Q63WW1
UniProtKB ID Q63WW1_BURPS
UniRef100 UniRef100_A3NRX8
UniRef50 UniRef50_P36967
UniRef90 UniRef90_A1V6W9

Product

Feature Type CDS
Coding Frame 1
Product Name
succinyl-CoA synthetase subunit alpha
Synonyms
Evidence for Translation
Charge (pH 7) -0.92
Kyte-Doolittle Hydrophobicity Value -0.034
Molecular Weight (kDa) 30765.3
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 552 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002506 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0780
Search term: sucD

Human Homologs

Ensembl 97, assembly GRCh38.p12
succinate-CoA ligase alpha subunit [Source:HGNC Symbol;Acc:HGNC:11449]
E-value: 2.4e-87
Percent Identity: 55.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268