Burkholderia pseudomallei K96243, BPSL0779 (sucC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0779
Name
sucC
Replicon chromosome 1
Genomic location 906374 - 907540 (+ strand)

Cross-References

RefSeq YP_107404.1
GI 53718418
Entrez 3093010
GI 53718418
INSDC CAH34771.1
NCBI Locus Tag BPSL0779
RefSeq YP_107404.1,GeneID
UniParc UPI000043AD56
UniProtKB Acc Q63WW2
UniProtKB ID SUCC_BURPS
UniRef100 UniRef100_A3MH60
UniRef50 UniRef50_Q9KA20
UniRef90 UniRef90_Q13UH9

Product

Feature Type CDS
Coding Frame 1
Product Name
succinyl-CoA synthetase subunit beta
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (45.6 kDa, pI 4.67, PMID:21960737)
Charge (pH 7) -8.84
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 41285.3
Isoelectric Point (pI) 5.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 537 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002507 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0779
Search term: sucC

Human Homologs

Ensembl 97, assembly GRCh38.p12
succinate-CoA ligase ADP-forming beta subunit [Source:HGNC Symbol;Acc:HGNC:11448]
E-value: 1.3e-96
Percent Identity: 48.3

Human Homologs

Ensembl 97, assembly GRCh38.p12
succinate-CoA ligase ADP-forming beta subunit [Source:HGNC Symbol;Acc:HGNC:11448]
E-value: 1.3e-96
Percent Identity: 48.3

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268