Burkholderia pseudomallei K96243, BPSL0687 (glpK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0687
Name
glpK
Replicon chromosome 1
Genomic location 782878 - 784380 (- strand)

Cross-References

RefSeq YP_107316.1
GI 53718330
Entrez 3092942
GI 53718330
INSDC CAH34680.1
NCBI Locus Tag BPSL0687
RefSeq YP_107316.1,GeneID
UniParc UPI000043ACFF
UniProtKB Acc Q63X50
UniProtKB ID GLPK_BURPS
UniRef100 UniRef100_Q63X50
UniRef50 UniRef50_O93623
UniRef90 UniRef90_Q63X50

Product

Feature Type CDS
Coding Frame 1
Product Name
glycerol kinase
Synonyms
Evidence for Translation
Charge (pH 7) -7.94
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 54533.3
Isoelectric Point (pI) 5.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 490 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002537 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0687
Search term: glpK
Search term: glycerol kinase

Human Homologs

Ensembl 97, assembly GRCh38.p12
glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289]
E-value: 8.5e-125
Percent Identity: 46.9

Human Homologs

Ensembl 97, assembly GRCh38.p12
glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289]
E-value: 8.5e-125
Percent Identity: 46.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268