Burkholderia pseudomallei K96243, BPSL0666

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0666
Name
Replicon chromosome 1
Genomic location 756967 - 757530 (- strand)

Cross-References

RefSeq YP_107295.1
GI 53718309
Entrez 3092787
GI 53718309
INSDC CAH34659.1
NCBI Locus Tag BPSL0666
RefSeq YP_107295.1,GeneID
UniParc UPI000043ACEA
UniProtKB Acc Q63X71
UniProtKB ID Q63X71_BURPS
UniRef100 UniRef100_A0A069B259
UniRef50 UniRef50_Q2T109
UniRef90 UniRef90_Q2T109

Product

Feature Type CDS
Coding Frame 1
Product Name
D,D-heptose 1,7-bisphosphate phosphatase
Synonyms
Evidence for Translation
Charge (pH 7) -2.17
Kyte-Doolittle Hydrophobicity Value -0.112
Molecular Weight (kDa) 20189.0
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4PNH HYDROLASE 05/23/14 Crystal structure of D,D-heptose 1,7-bisphosphate phosphatase from Burkholderia Thailandensis BURKHOLDERIA THAILANDENSIS 2.66 X-RAY DIFFRACTION 96.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 367 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002558 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0666

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268