Burkholderia pseudomallei K96243, BPSL0663 (gloA)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL0663
Name	gloA
Replicon	chromosome 1
Genomic location	754617 - 755006 (+ strand)

Cross-References

RefSeq	YP_107292.1
GI	53718306
Entrez	3092375
GI	53718306
INSDC	CAH34656.1
NCBI Locus Tag	BPSL0663
RefSeq	YP_107292.1,GeneID
UniParc	UPI000043ACE7
UniProtKB Acc	Q63X74
UniProtKB ID	Q63X74_BURPS
UniRef100	UniRef100_Q3JVW4
UniRef50	UniRef50_Q3JVW4
UniRef90	UniRef90_Q3JVW4

Product

Feature Type	CDS
Coding Frame	1
Product Name	lactoylglutathione lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.60
Kyte-Doolittle Hydrophobicity Value	-0.477
Molecular Weight (kDa)	14733.7
Isoelectric Point (pI)	6.51

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 369 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002561 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL0663 Search term: gloA Search term: lactoylglutathione lyase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000460634 glyoxalase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:14111] E-value: 7.3e-12 Percent Identity: 29.2
Ensembl 97, assembly GRCh38.p12	ENSP00000301329 glyoxalase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:14111] E-value: 7.3e-12 Percent Identity: 29.2

References