Burkholderia pseudomallei K96243, BPSL0659

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0659
Name
Replicon chromosome 1
Genomic location 749757 - 751109 (+ strand)

Cross-References

RefSeq YP_107288.1
GI 53718302
Entrez 3094814
GI 53718302
INSDC CAH34652.1
NCBI Locus Tag BPSL0659
RefSeq YP_107288.1,GeneID
UniParc UPI0000EAE04B
UniProtKB Acc Q63X78
UniProtKB ID SURA_BURPS
UniRef100 UniRef100_Q63X78
UniRef50 UniRef50_Q63X78
UniRef90 UniRef90_Q63X78

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidyl-prolyl cis-trans isomerase
Synonyms
Evidence for Translation
Charge (pH 7) 1.98
Kyte-Doolittle Hydrophobicity Value -0.400
Molecular Weight (kDa) 49145.2
Isoelectric Point (pI) 8.72

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 425 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002564 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0659

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268