Burkholderia pseudomallei K96243, BPSL0539

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0539
Name
Replicon chromosome 1
Genomic location 590427 - 592436 (+ strand)

Cross-References

RefSeq YP_107164.1
GI 53718178
Entrez 3092679
GI 53718178
INSDC CAH34528.1
NCBI Locus Tag BPSL0539
RefSeq YP_107164.1,GeneID
UniParc UPI000043AC67
UniProtKB Acc Q63XK1
UniProtKB ID Q63XK1_BURPS
UniRef100 UniRef100_A0A095HPS0
UniRef50 UniRef50_G0EUR2
UniRef90 UniRef90_Q3JW69

Product

Feature Type CDS
Coding Frame 1
Product Name
sodium/hydrogen exchanger family protein
Synonyms
Evidence for Translation
Charge (pH 7) -3.15
Kyte-Doolittle Hydrophobicity Value 0.536
Molecular Weight (kDa) 72324.2
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 519 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002636 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0539

Human Homologs

Ensembl 97, assembly GRCh38.p12
transmembrane and coiled-coil domains 3 [Source:HGNC Symbol;Acc:HGNC:20329]
E-value: 1.2e-20
Percent Identity: 27.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268