Burkholderia pseudomallei K96243, BPSL0521 (prs)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0521
Name
prs
Replicon chromosome 1
Genomic location 574124 - 575080 (- strand)

Cross-References

RefSeq YP_107147.1
GI 53718161
Entrez 3093690
GI 53718161
INSDC CAH34511.1
NCBI Locus Tag BPSL0521
RefSeq YP_107147.1,GeneID
UniParc UPI000043AC56
UniProtKB Acc Q63XL8
UniProtKB ID Q63XL8_BURPS
UniRef100 UniRef100_A0A069B4F4
UniRef50 UniRef50_Q89DJ1
UniRef90 UniRef90_Q2T1B7

Product

Feature Type CDS
Coding Frame 1
Product Name
ribose-phosphate pyrophosphokinase
Synonyms
Evidence for Translation
Charge (pH 7) -1.43
Kyte-Doolittle Hydrophobicity Value 0.166
Molecular Weight (kDa) 34210.3
Isoelectric Point (pI) 6.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3DAH TRANSFERASE 05/29/08 2.3 A crystal structure of ribose-phosphate pyrophosphokinase from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.3 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 661 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002653 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0521
Search term: prs

Human Homologs

Ensembl 97, assembly GRCh38.p12
phosphoribosyl pyrophosphate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:9465]
E-value: 4.2e-77
Percent Identity: 47.8

References

No references are associated with this feature.