Burkholderia pseudomallei K96243, BPSL0446 (secB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0446
Name
secB
Replicon chromosome 1
Genomic location 485609 - 486088 (+ strand)

Cross-References

RefSeq YP_107071.1
GI 53718085
Entrez 3091642
GI 53718085
INSDC CAH34434.1
NCBI Locus Tag BPSL0446
RefSeq YP_107071.1,GeneID
UniParc UPI000043AC0B
UniProtKB Acc Q63XU4
UniProtKB ID SECB_BURPS
UniRef100 UniRef100_A3MQ26
UniRef50 UniRef50_A1VKS9
UniRef90 UniRef90_A3MQ26

Product

Feature Type CDS
Coding Frame 1
Product Name
preprotein translocase subunit SecB
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (19.3 kDa, pI 4.46, PMID:21960737)
Charge (pH 7) -8.83
Kyte-Doolittle Hydrophobicity Value -0.064
Molecular Weight (kDa) 17671.0
Isoelectric Point (pI) 4.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 217 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002700 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0446
Search term: secB

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268