Burkholderia pseudomallei K96243, BPSL0373 (aceK)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL0373
Name	aceK
Replicon	chromosome 1
Genomic location	402273 - 404084 (- strand)

Cross-References

RefSeq	YP_106999.1
GI	53718013
Entrez	3092419
GI	53718013
INSDC	CAH34361.1
NCBI Locus Tag	BPSL0373
RefSeq	YP_106999.1,GeneID
UniParc	UPI000043ABC3
UniProtKB Acc	Q63Y16
UniProtKB ID	ACEK_BURPS
UniRef100	UniRef100_A3MNH1
UniRef50	UniRef50_Q0BBE2
UniRef90	UniRef90_Q2T1P5

Product

Feature Type	CDS
Coding Frame	1
Product Name	bifunctional isocitrate dehydrogenase kinase/phosphatase
Synonyms
Evidence for Translation
Charge (pH 7)	-14.89
Kyte-Doolittle Hydrophobicity Value	-0.298
Molecular Weight (kDa)	69892.9
Isoelectric Point (pI)	5.78

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 74 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002766 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL0373 Search term: aceK Search term: bifunctional isocitrate dehydrogenase kinase/phosphatase

Human Homologs

References