Burkholderia pseudomallei K96243, BPSL0371

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0371
Name
Replicon chromosome 1
Genomic location 400265 - 401458 (- strand)

Cross-References

RefSeq YP_106997.1
GI 53718011
Entrez 3092743
GI 53718011
INSDC CAH34359.1
NCBI Locus Tag BPSL0371
RefSeq YP_106997.1,GeneID
UniParc UPI000043ABC1
UniProtKB Acc Q63Y18
UniProtKB ID Q63Y18_BURPS
UniRef100 UniRef100_A0A069B1D8
UniRef50 UniRef50_D7HZ68
UniRef90 UniRef90_A1V825

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyl-CoA acetyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) 0.51
Kyte-Doolittle Hydrophobicity Value 0.153
Molecular Weight (kDa) 40914.7
Isoelectric Point (pI) 7.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 476 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005138 (641 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0371

Human Homologs

Ensembl 97, assembly GRCh38.p12
acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93]
E-value: 1.2e-81
Percent Identity: 47.6

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268