Burkholderia pseudomallei K96243, BPSL0371

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0371
Name
Replicon chromosome 1
Genomic location 400265 - 401458 (- strand)

Cross-References

RefSeq YP_106997.1
GI 53718011
Entrez 3092743
GI 53718011
INSDC CAH34359.1
NCBI Locus Tag BPSL0371
RefSeq YP_106997.1,GeneID
UniParc UPI000043ABC1
UniProtKB Acc Q63Y18
UniProtKB ID Q63Y18_BURPS
UniRef100 UniRef100_A0A069B1D8
UniRef50 UniRef50_D7HZ68
UniRef90 UniRef90_A1V825

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyl-CoA acetyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) 0.51
Kyte-Doolittle Hydrophobicity Value 0.153
Molecular Weight (kDa) 40914.7
Isoelectric Point (pI) 7.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 476 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005138 (641 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0371

Human Homologs

Ensembl 97, assembly GRCh38.p12
acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93]
E-value: 1.2e-81
Percent Identity: 47.6

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268