Burkholderia pseudomallei K96243, BPSL0273 (flgE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0273
Name
flgE
Replicon chromosome 1
Genomic location 284510 - 285751 (+ strand)

Cross-References

RefSeq YP_106900.1
GI 53717914
Entrez 3093786
GI 53717914
INSDC CAH34261.1
NCBI Locus Tag BPSL0273
RefSeq YP_106900.1,GeneID
UniParc UPI000043AB61
UniProtKB Acc Q63YB5
UniProtKB ID Q63YB5_BURPS
UniRef100 UniRef100_A0A069B400
UniRef50 UniRef50_I1WNH7
UniRef90 UniRef90_I1WNH7

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar hook protein FlgE
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -3.78
Kyte-Doolittle Hydrophobicity Value -0.217
Molecular Weight (kDa) 42491.4
Isoelectric Point (pI) 4.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

Virulence Evidence

Source 1
Database VFDB : VF0430
Category Flagella
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 317 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002847 (647 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0273
Search term: flgE

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268