Burkholderia pseudomallei K96243, BPSL0224

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0224
Name
Replicon chromosome 1
Genomic location 233741 - 235384 (+ strand)

Cross-References

RefSeq YP_106852.1
GI 53717866
Entrez 3092388
GI 53717866
INSDC CAH34212.1
NCBI Locus Tag BPSL0224
RefSeq YP_106852.1,GeneID
UniParc UPI000043AB33
UniProtKB Acc Q63YG3
UniProtKB ID Q63YG3_BURPS
UniRef100 UniRef100_A0A097XV15
UniRef50 UniRef50_A9ABT4
UniRef90 UniRef90_Q2T247

Product

Feature Type CDS
Coding Frame 1
Product Name
GMC oxidoreductase
Synonyms
Evidence for Translation
Charge (pH 7) 3.83
Kyte-Doolittle Hydrophobicity Value -0.154
Molecular Weight (kDa) 58702.0
Isoelectric Point (pI) 7.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 213 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002895 (649 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0224

Human Homologs

Ensembl 97, assembly GRCh38.p12
choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288]
E-value: 2.7e-108
Percent Identity: 42.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268