Burkholderia pseudomallei K96243, BPSL0189 (gatB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0189
Name
gatB
Replicon chromosome 1
Genomic location 195126 - 196598 (+ strand)

Cross-References

RefSeq YP_106817.1
GI 53717831
Entrez 3092491
GI 53717831
INSDC CAH34176.1
NCBI Locus Tag BPSL0189
RefSeq YP_106817.1,GeneID
UniParc UPI000043AB10
UniProtKB Acc Q63YJ8
UniProtKB ID GATB_BURPS
UniRef100 UniRef100_Q63YJ8
UniRef50 UniRef50_Q146Y4
UniRef90 UniRef90_Q63YJ8

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartyl/glutamyl-tRNA amidotransferase subunit B
Synonyms
Evidence for Translation
Charge (pH 7) -8.89
Kyte-Doolittle Hydrophobicity Value -0.207
Molecular Weight (kDa) 53336.3
Isoelectric Point (pI) 5.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 566 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002935 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0189
Search term: gatB

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutamyl-tRNA amidotransferase subunit B [Source:HGNC Symbol;Acc:HGNC:8849]
E-value: 4.0e-95
Percent Identity: 39.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268