Burkholderia pseudomallei K96243, BPSL0118

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0118
Name
Replicon chromosome 1
Genomic location 131843 - 134452 (- strand)

Cross-References

RefSeq YP_106745.1
GI 53717759
Entrez 3092351
GI 53717759
INSDC CAH34104.1
NCBI Locus Tag BPSL0118
RefSeq YP_106745.1,GeneID
UniParc UPI000043AAC9
UniProtKB Acc Q63YS0
UniProtKB ID Q63YS0_BURPS
UniRef100 UniRef100_A3NQ18
UniRef50 UniRef50_A1V7A2
UniRef90 UniRef90_A1V7A2

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA topoisomerase III
Synonyms
Evidence for Translation
Charge (pH 7) 16.31
Kyte-Doolittle Hydrophobicity Value -0.495
Molecular Weight (kDa) 96944.9
Isoelectric Point (pI) 9.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 665 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002958 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0118

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268