Burkholderia cenocepacia H111, I35_RS25090 (tecA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
GCF_000236215.2|latest
Locus Tag
I35_RS25090
NCBI Old Locus TagI35_4213%2CI35_5735
Name
tecA
Replicon chromosome 2
Genomic location 1957238 - 1957717 (- strand)

Cross-References

RefSeq WP_006496925.1
GI 493543064
NCBI Locus Tag I35_RS25090
NCBI Old Locus Tag I35_4213%2CI35_5735
RefSeq WP_006496925.1

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system effector protein TecA
Product Name Confidence: Class 2
Synonyms urea amidohydrolase
Evidence for Translation
Charge (pH 7) 2.91
Kyte-Doolittle Hydrophobicity Value -0.017
Molecular Weight (kDa) 17057.2
Isoelectric Point (pI) 9.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 2
sequence similarity evidence used in manual assertion
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006635 (186 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS25090
Search term: tecA

References

A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.
Aubert DF, Xu H, Yang J, Shi X, Gao W, Li L, Bisaro F, Chen S, Valvano MA, Shao F
Cell Host Microbe 2016 May 11;19(5):664-74
PubMed ID: 27133449