Burkholderia cenocepacia H111, I35_RS21115 (bceR)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
Locus Tag
NCBI Old Locus TagI35_2569%2CI35_4927
Replicon chromosome 2
Genomic location 1029719 - 1032187 (+ strand)
CommentMember of the bce-II gene cluster
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis.
CommentNote that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).


RefSeq WP_006495939.1
GI 493542072
NCBI Locus Tag I35_RS21115
NCBI Old Locus Tag I35_2569%2CI35_4927
RefSeq WP_006495939.1


Feature Type CDS
Coding Frame 1
Product Name
glycosyl transferase family 1
Product Name Confidence: Class 2
Evidence for Translation
Charge (pH 7) 11.60
Kyte-Doolittle Hydrophobicity Value 0.016
Molecular Weight (kDa) 89514.8
Isoelectric Point (pI) 8.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003106 (652 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS21115
Search term: bceR

Human Homologs


Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863