Burkholderia cenocepacia H111, I35_RS15945

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
GCF_000236215.2|latest
Locus Tag
I35_RS15945
NCBI Old Locus TagI35_1772%2CI35_3191
Name
Replicon chromosome 1
Genomic location 3438080 - 3438712 (- strand)

Cross-References

RefSeq WP_006495383.1
GI 493541511
NCBI Locus Tag I35_RS15945
NCBI Old Locus Tag I35_1772%2CI35_3191
RefSeq WP_006495383.1

Product

Feature Type CDS
Coding Frame 1
Product Name
7-carboxy-7-deazaguanine synthase
Synonyms
Evidence for Translation
Charge (pH 7) -7.26
Kyte-Doolittle Hydrophobicity Value -0.141
Molecular Weight (kDa) 23163.2
Isoelectric Point (pI) 4.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4NJG LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxypterin BURKHOLDERIA MULTIVORANS 2.598 X-RAY DIFFRACTION 98.1
4NJH LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxy-5,6,7,8-tetrahydropterin BURKHOLDERIA MULTIVORANS 1.898 X-RAY DIFFRACTION 98.1
4NJI LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Mg2+ BURKHOLDERIA MULTIVORANS 2.197 X-RAY DIFFRACTION 98.1
4NJJ LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Manganese(II) BURKHOLDERIA MULTIVORANS 2.7 X-RAY DIFFRACTION 98.1
4NJK LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 7-carboxy-7-deazaguanine, and Mg2+ BURKHOLDERIA MULTIVORANS 1.911 X-RAY DIFFRACTION 98.1

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002946 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS15945

Human Homologs

References

No references are associated with this feature.