Burkholderia cenocepacia H111, I35_RS01730 (tssD)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
Locus Tag
NCBI Old Locus TagI35_0334%2CI35_0383
Synonym: hcp
Replicon chromosome 1
Genomic location 353973 - 354476 (+ strand)
CommentPart of the T6SS gene cluster


RefSeq WP_006477093.1
GI 493523014
NCBI Locus Tag I35_RS01730
NCBI Old Locus Tag I35_0334%2CI35_0383
RefSeq WP_006477093.1


Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssD
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 0.88
Kyte-Doolittle Hydrophobicity Value -0.526
Molecular Weight (kDa) 18422.6
Isoelectric Point (pI) 7.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence
Extracellular Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000368 (644 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS01730
Search term: tssD


Vibrio cholerae Hcp, a secreted protein coregulated with HlyA.
Williams SG, Varcoe LT, Attridge SR, Manning PA
Infect Immun 1996 Jan;64(1):283-9
PubMed ID: 8557353
A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149