Burkholderia cenocepacia H111, I35_RS01720 (tssB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
GCF_000236215.2|latest
Locus Tag
I35_RS01720
NCBI Old Locus TagI35_0332%2CI35_0385
Name
tssB
Synonym: bcsL
Replicon chromosome 1
Genomic location 351881 - 352396 (+ strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_006484395.1
GI 493530383
NCBI Locus Tag I35_RS01720
NCBI Old Locus Tag I35_0332%2CI35_0385
RefSeq WP_006484395.1

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssB
Product Name Confidence: Class 1
Synonyms type VI secretion protein
Evidence for Translation
Charge (pH 7) -3.99
Kyte-Doolittle Hydrophobicity Value -0.646
Molecular Weight (kDa) 19245.7
Isoelectric Point (pI) 4.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000366 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS01720
Search term: tssB

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
BcsKC is an essential protein for the type VI secretion system activity in Burkholderia cenocepacia that forms an outer membrane complex with BcsLB.
Aubert D, MacDonald DK, Valvano MA
J Biol Chem 2010 Nov 12;285(46):35988-98
PubMed ID: 20729192
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149