Burkholderia ambifaria AMMD, BAMB_RS27645 (bceA)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia ambifaria AMMD - Assembly GCF_000203915.1
Locus Tag
NCBI Old Locus TagBamb_5545
Synonym: cpsB
Replicon chromosome 2
Genomic location 2616048 - 2617574 (- strand)
CommentMember of the bce-I gene cluster


RefSeq WP_011660455.1
GI 499979737
NCBI Locus Tag BAMB_RS27645
NCBI Old Locus Tag Bamb_5545
RefSeq WP_011660455.1


Feature Type CDS
Coding Frame NA
Product Name
Product Name Confidence: Class 2
Synonyms mannose-1-phosphate guanylyltransferase
Evidence for Translation
Charge (pH 7) -9.80
Kyte-Doolittle Hydrophobicity Value -0.167
Molecular Weight (kDa) 55213.0
Isoelectric Point (pI) 6.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003312 (1226 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: BAMB_RS27645
Search term: bceA
Search term: BceA

Human Homologs


Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Wopperer J, Eberl L, Sá-Correia I, Leitão JH
Biochem Biophys Res Commun 2007 Feb 2;353(1):200-6
PubMed ID: 17184737
Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Leitão JH
Appl Microbiol Biotechnol 2008 Oct;80(6):1015-22
PubMed ID: 18668237