Burkholderia ambifaria AMMD, BAMB_RS16855

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia ambifaria AMMD - Assembly GCF_000203915.1
GCF_000203915.1|latest
Locus Tag
BAMB_RS16855
NCBI Old Locus TagBamb_3343
Name
Replicon chromosome 2
Genomic location 134792 - 135859 (+ strand)

Cross-References

RefSeq WP_011658380.1
GI 499977662
NCBI Locus Tag BAMB_RS16855
NCBI Old Locus Tag Bamb_3343
RefSeq WP_011658380.1

Product

Feature Type CDS
Coding Frame NA
Product Name
3-isopropylmalate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -8.85
Kyte-Doolittle Hydrophobicity Value -0.084
Molecular Weight (kDa) 38207.3
Isoelectric Point (pI) 4.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4IWH OXIDOREDUCTASE 01/23/13 Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei BURKHOLDERIA THAILANDENSIS 1.75 X-RAY DIFFRACTION 98.0
4XXV OXIDOREDUCTASE 01/31/15 Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD BURKHOLDERIA THAILANDENSIS 1.7 X-RAY DIFFRACTION 98.0

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003088 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BAMB_RS16855

Human Homologs

Ensembl 97, assembly GRCh38.p12
isocitrate dehydrogenase 3 (NAD(+)) alpha [Source:HGNC Symbol;Acc:HGNC:5384]
E-value: 7.3e-30
Percent Identity: 31.0

References

No references are associated with this feature.