Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS16510 (hmuR)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS16510
|
| NCBI Old Locus Tag | BURCENK562V_C4843 |
| Name |
hmuR
|
| Replicon | ctg7180000002940B |
| Genomic location | 2388068 - 2390341 (+ strand) |
| Comment | Member of the hemin uptake (hmu) operon |
Cross-References
| RefSeq | WP_006489211.1 |
| GI | 493535257 |
| GI | 493535257 |
| NCBI Locus Tag | BURCENK562V_RS16510 |
| NCBI Old Locus Tag | BURCENK562V_C4843 |
| RefSeq | WP_006489211.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
TonB-dependent outer membrane heme receptor HmuR
|
| Synonyms |
membrane protein |
| Evidence for Translation | |
| Charge (pH 7) | 7.06 |
| Kyte-Doolittle Hydrophobicity Value | -0.338 |
| Molecular Weight (kDa) | 82162.9 |
| Isoelectric Point (pI) | 8.81 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG004242 (596 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS16510
Search term: hmuR
Search term: TonB-dependent outer membrane heme receptor HmuR
|
Human Homologs
References
|
The Small Protein HemP Is a Transcriptional Activator for the Hemin Uptake Operon in Burkholderia multivorans ATCC 17616.
Sato T, Nonoyama S, Kimura A, Nagata Y, Ohtsubo Y, Tsuda M
Appl Environ Microbiol 2017 Aug 15;83(16)
PubMed ID: 28625994
|
|
Burkholderia pseudomallei known siderophores and hemin uptake are dispensable for lethal murine melioidosis.
Kvitko BH, Goodyear A, Propst KL, Dow SW, Schweizer HP
PLoS Negl Trop Dis 2012;6(6):e1715
PubMed ID: 22745846
|