Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS08350 (bceN)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS08350
|
| NCBI Old Locus Tag | BURCENK562V_C3031 |
| Name |
bceN
|
| Replicon | ctg7180000002940B |
| Genomic location | 535345 - 536391 (- strand) |
| Comment | Member of the bce-II gene cluster |
Cross-References
| RefSeq | WP_006491261.1 |
| GI | 493537335 |
| EC Number | 4.2.1.47 |
| GI | 493537335 |
| NCBI Locus Tag | BURCENK562V_RS08350 |
| NCBI Old Locus Tag | BURCENK562V_C3031 |
| RefSeq | WP_006491261.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
GDP-D-mannose 4,6-dehydratase BceN
|
| Synonyms |
GDP-D-mannose dehydratase |
| Evidence for Translation | |
| Charge (pH 7) | -0.61 |
| Kyte-Doolittle Hydrophobicity Value | -0.341 |
| Molecular Weight (kDa) | 38958.9 |
| Isoelectric Point (pI) | 6.80 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG003102 (653 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS08350
Search term: bceN
Search term: GDP-D-mannose 4,6-dehydratase BceN
|
Human Homologs
|
Ensembl
97, assembly
GRCh38.p12
|
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value:
9.5e-99
Percent Identity:
53.0
|
References
|
Biochemical and functional studies on the Burkholderia cepacia complex bceN gene, encoding a GDP-D-mannose 4,6-dehydratase.
Sousa SA, Feliciano JR, Pinheiro PF, Leitão JH
PLoS One 2013;8(2):e56902
PubMed ID: 23460819
|
|
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
|