Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS08345 (bceM)

Cytoplasmic Membrane
Outer Membrane

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
NCBI Old Locus TagBURCENK562V_C3030
Replicon ctg7180000002940B
Genomic location 534393 - 535358 (- strand)
CommentMember of the bce-II gene cluster


RefSeq WP_006491265.1
GI 493537339
GI 493537339
NCBI Locus Tag BURCENK562V_RS08345
NCBI Old Locus Tag BURCENK562V_C3030
RefSeq WP_006491265.1


Feature Type CDS
Coding Frame 1
Product Name
GDP-6-deoxy-D-lyxo-4-hexulose reductase BceM
Synonyms GDP-6-deoxy-D-lyxo-4-hexulose reductase
Evidence for Translation
Charge (pH 7) 2.14
Kyte-Doolittle Hydrophobicity Value -0.043
Molecular Weight (kDa) 34430.8
Isoelectric Point (pI) 8.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4LW8 ISOMERASE 07/26/13 Crystal structure of a putative epimerase from Burkholderia cenocepacia J2315 BURKHOLDERIA CENOCEPACIA 2.1 X-RAY DIFFRACTION 100.0

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000738 (646 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: bceM

Human Homologs


Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863