Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS07600 (bceA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS07600
NCBI Old Locus TagBURCENK562V_C2864
Name
bceA
Synonym: cpsB
Replicon ctg7180000002940B
Genomic location 363683 - 365224 (- strand)
CommentMember of the bce-I gene cluster

Cross-References

RefSeq WP_012493179.1
GI 501469734
GI 501469734
NCBI Locus Tag BURCENK562V_RS07600
NCBI Old Locus Tag BURCENK562V_C2864
RefSeq WP_012493179.1

Product

Feature Type CDS
Coding Frame 1
Product Name
bifunctional exopolysaccharide biosynthesis protein (phosphomannose isomerase and GDP-D-mannose pyrophosphorylase) BceA
Product Name Confidence: Class 1
Synonyms bifunctional exopolysaccharide biosynthesis protein (phosphomannose isomerase and GDP-D-mannose pyrophosphorylase)
Evidence for Translation
Charge (pH 7) -7.32
Kyte-Doolittle Hydrophobicity Value -0.144
Molecular Weight (kDa) 55715.7
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003312 (1226 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: bceA

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Wopperer J, Eberl L, Sá-Correia I, Leitão JH
Biochem Biophys Res Commun 2007 Feb 2;353(1):200-6
PubMed ID: 17184737
Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Leitão JH
Appl Microbiol Biotechnol 2008 Oct;80(6):1015-22
PubMed ID: 18668237